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Chemical structure of AC-73

GC60550

AC-73

Also known as 3-[1-hydroxy-2-[(4-phenylphenyl)methylamino]ethyl]phenol

AC-73 is a first specific, orally active inhibitor of cluster of differentiation 147 (CD147), which specifically disrupts CD147 dimerization, thereby mainly suppressing the CD147/ERK1/2/STAT3/MMP-2 pathways· AC-73 inhibits the motility and invasion of hepatocellular carcinoma cells· AC-73 is also an anti-proliferative drug and an inducer of autophagy in leukemic cells

ChemicalCAS775294-71-8MW319.4FormulaC21H21NO2
CAS number
775294-71-8
Molecular weight
319.4
Formula
C21H21NO2
Solubility
DMSO: ≥ 250 mg/mL (782·72 mM)
InChIKey
UECKKYNEEBRMIL-UHFFFAOYSA-N
Catalogue number
GC60550
Brand
GLPBIO
Computed properties PubChem CID 2989791 · XLogP 2.8 · TPSA 52.5 Ų · H-bond donors 3
XLogP
2.8
TPSA
52.5 Ų
H-bond donors
3
H-bond acceptors
3
Rotatable bonds
6
Heavy atoms
24

SMILES C1=CC=C(C=C1)C2=CC=C(C=C2)CNCC(C3=CC(=CC=C3)O)O

Computed descriptors from PubChem (CID 2989791), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.