Loading...
Chemical structure of SKI V

GC60339

SKI V

Also known as (2Z)-2-[(3,4-dihydroxyphenyl)methylidene]-1-benzofuran-3-one

SKI V is a noncompetitive and potent non-lipid sphingosine kinase (SPHK; SK) inhibitor with an IC50 of 2 μM for GST-hSK· SKI V potently inhibits PI3K with an IC50 of 6 μM for hPI3k· SKI V decreases formation of the mitogenic second messenger sphingosine-1-phosphate (S1P)· SKI V induces apoptosis and has antitumor activity

ChemicalCAS24418-86-8MW254.24FormulaC15H10O4
CAS number
24418-86-8
Molecular weight
254.24
Formula
C15H10O4
Solubility
DMSO： 250 mg/mL (983·32 mM)
InChIKey
HCBULGQMULJTCM-ZSOIEALJSA-N
Catalogue number
GC60339
Brand
GLPBIO
Computed properties PubChem CID 5793932 · XLogP 2.9 · TPSA 66.8 Ų · H-bond donors 2
XLogP
2.9
TPSA
66.8 Ų
H-bond donors
2
H-bond acceptors
4
Rotatable bonds
1
Heavy atoms
19

SMILES C1=CC=C2C(=C1)C(=O)/C(=C/C3=CC(=C(C=C3)O)O)/O2

Computed descriptors from PubChem (CID 5793932), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.