Loading...
Chemical structure of Ribociclib D6

GC60324

Ribociclib D6

Also known as 7-cyclopentyl-2-[(5-piperazin-1-yl-2-pyridinyl)amino]-N,N-bis(trideuteriomethyl)pyrrolo[2,3-d]pyrimidine-6-carboxamide

Ribociclib D6 (LEE011 D6) is a deuterium labeled Ribociclib· Ribociclib is a highly specific CDK4/6 inhibitor with IC50 values of 10 nM and 39 nM, respectively, and is over 1,000-fold less potent against the cyclin B/CDK1 complex

ChemicalCAS1328934-40-2MW440.57FormulaC23H24D6N8O
CAS number
1328934-40-2
Molecular weight
440.57
Formula
C23H24D6N8O
InChIKey
RHXHGRAEPCAFML-WFGJKAKNSA-N
Catalogue number
GC60324
Brand
GLPBIO
Computed properties PubChem CID 53348205 · XLogP 2.2 · TPSA 91.2 Ų · H-bond donors 2
XLogP
2.2
TPSA
91.2 Ų
H-bond donors
2
H-bond acceptors
7
Rotatable bonds
5
Heavy atoms
32

SMILES [2H]C([2H])([2H])N(C(=O)C1=CC2=CN=C(N=C2N1C3CCCC3)NC4=NC=C(C=C4)N5CCNCC5)C([2H])([2H])[2H]

Computed descriptors from PubChem (CID 53348205), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.