GC37529
LEE011 succinate hydrate
Also listed as Ribociclib succinate hydrate
Ribociclib succinate hydrate (LEE011 succinate hydrate) is a highly specific CDK4/6 inhibitor with IC50 values of 10 nM and 39 nM, respectively, and is over 1,000-fold less potent against the cyclin B/CDK1 complex
ChemicalCAS1374639-79-8MW570.64FormulaC27H38N8O6
- CAS number
- 1374639-79-8
- Molecular weight
- 570.64
- Formula
- C27H38N8O6
- Solubility
- DMSO： ≥ 19 mg/mL (33·30 mM)
- InChIKey
- PZJOFPMHNJJJSC-UHFFFAOYSA-N
- Catalogue number
- GC37529
- Brand
- GLPBIO
Computed properties PubChem CID 127255617 · TPSA 167 Ų · H-bond donors 5 · H-bond acceptors 12
- TPSA
- 167 Ų
- H-bond donors
- 5
- H-bond acceptors
- 12
- Rotatable bonds
- 8
- Heavy atoms
- 41
SMILES CN(C)C(=O)C1=CC2=CN=C(N=C2N1C3CCCC3)NC4=NC=C(C=C4)N5CCNCC5.C(CC(=O)O)C(=O)O.O
Computed descriptors from PubChem (CID 127255617), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.
Ordering in Israel
- Lead time
- Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
- Pricing
- Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
- Documents
- Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
- Who we serve
- Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.
- Questions
- WhatsApp · +972-55-990-7576 · orders@labo.co.il