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Chemical structure of RET V804M-IN-1

GC60320

RET V804M-IN-1

Also known as 4-[5-(pyridin-3-ylmethylamino)pyrazolo[1,5-a]pyrimidin-3-yl]benzamide

RET V804M-IN-1 (compound 5) is a wt-RET -selective inhibitors of RETV804M kinase, with an IC50 of 20 nM

ChemicalCAS2414909-94-5MW344.37FormulaC19H16N6O
CAS number
2414909-94-5
Molecular weight
344.37
Formula
C19H16N6O
Solubility
DMSO: 125 mg/mL (362·98 mM)
InChIKey
LMGXQBQAUALFTB-UHFFFAOYSA-N
Catalogue number
GC60320
Brand
GLPBIO
Computed properties PubChem CID 145994823 · XLogP 1.6 · TPSA 98.2 Ų · H-bond donors 2
XLogP
1.6
TPSA
98.2 Ų
H-bond donors
2
H-bond acceptors
5
Rotatable bonds
5
Heavy atoms
26

SMILES C1=CC(=CN=C1)CNC2=NC3=C(C=NN3C=C2)C4=CC=C(C=C4)C(=O)N

Computed descriptors from PubChem (CID 145994823), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

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Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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