GB40343
RET Inhibitor 2667
Also known as N-[(1S)-1-[6-(4-fluoropyrazol-1-yl)-3-pyridinyl]ethyl]-3-methyl-5-[4-methyl-6-[(5-methyl-1H-pyrazol-3-yl)amino]pyrimidin-2-yl]pyridine-2-carboxamide
Potent RET inhibitor (IC50 value <10 nM) with activity against wild-type RET and its mutants
ChemicalCAS1980023-80-0MW512.54FormulaC26H25FN10O
- CAS number
- 1980023-80-0
- Molecular weight
- 512.54
- Formula
- C26H25FN10O
- InChIKey
- DAFQECVJVSAYPF-KRWDZBQOSA-N
- Catalogue number
- GB40343
- Brand
- GLPBIO
Computed properties PubChem CID 122487497 · XLogP 3.3 · TPSA 139 Ų · H-bond donors 3
- XLogP
- 3.3
- TPSA
- 139 Ų
- H-bond donors
- 3
- H-bond acceptors
- 9
- Rotatable bonds
- 7
- Heavy atoms
- 38
SMILES CC1=CC(=CN=C1C(=O)N[C@@H](C)C2=CN=C(C=C2)N3C=C(C=N3)F)C4=NC(=CC(=N4)NC5=NNC(=C5)C)C
Computed descriptors from PubChem (CID 122487497), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.
Ordering in Israel
- Lead time
- Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
- Pricing
- Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
- Documents
- Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
- Who we serve
- Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.
- Questions
- WhatsApp · +972-55-990-7576 · orders@labo.co.il