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Chemical structure of AV-153 free base

GC60062

AV-153 free base

Also known as 3,5-bis(ethoxycarbonyl)-2,6-dimethyl-1,4-dihydropyridine-4-carboxylic acid

AV-153 free base, a 1,4-dihydropyridine (1,4-DHP) derivative, is an antimutagenic· AV-153 free base intercalates to DNA in a single strand break and reduces DNA damage, stimulates DNA repair in human cells in vitro· AV-153 free base interacts with thymine and cytosine and has an influence on poly(ADP)ribosylation· AV-153 free base has anti-cancer activity

ChemicalCAS19350-66-4MW297.3FormulaC14H19NO6
CAS number
19350-66-4
Molecular weight
297.3
Formula
C14H19NO6
Solubility
DMSO： 250 mg/mL (840·90 mM)
InChIKey
USGQSNVLGQWBEC-UHFFFAOYSA-N
Catalogue number
GC60062
Brand
GLPBIO
Computed properties PubChem CID 168683 · XLogP 1.1 · TPSA 102 Ų · H-bond donors 2
XLogP
1.1
TPSA
102 Ų
H-bond donors
2
H-bond acceptors
7
Rotatable bonds
7
Heavy atoms
21

SMILES CCOC(=O)C1=C(NC(=C(C1C(=O)O)C(=O)OCC)C)C

Computed descriptors from PubChem (CID 168683), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

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