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Chemical structure of ASP4132

GC60058

ASP4132

Also known as [6-[1-[(6-methoxy-3-pyridinyl)methyl]piperidin-4-yl]-1H-benzimidazol-2-yl]-[4-[[4-(trifluoromethyl)phenyl]methyl]piperazin-1-yl]methanone;bis(4-methylbenzenesulfonic acid)

ASP4132 is an orally active, potent AMPK activator with an EC50 of 18 nM· ASP4132 has anti-cancer activity and makes tumor regression in breast cancer xenograft mouse models

ChemicalCAS1640294-30-9MW937.06FormulaC46H51F3N6O8S2
CAS number
1640294-30-9
Molecular weight
937.06
Formula
C46H51F3N6O8S2
Solubility
DMSO： 250 mg/mL (266·79 mM); Methanol： 8·33 mg/mL (8·89 mM)
InChIKey
KDMGCEXVMOJAAC-UHFFFAOYSA-N
Catalogue number
GC60058
Brand
GLPBIO
Computed properties PubChem CID 146673134 · TPSA 203 Ų · H-bond donors 3 · H-bond acceptors 15
TPSA
203 Ų
H-bond donors
3
H-bond acceptors
15
Rotatable bonds
9
Heavy atoms
65

SMILES CC1=CC=C(C=C1)S(=O)(=O)O.CC1=CC=C(C=C1)S(=O)(=O)O.COC1=NC=C(C=C1)CN2CCC(CC2)C3=CC4=C(C=C3)N=C(N4)C(=O)N5CCN(CC5)CC6=CC=C(C=C6)C(F)(F)F

Computed descriptors from PubChem (CID 146673134), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.