Loading...
Chemical structure of ASP5878

GC34476

ASP5878

Also known as 2-[4-[[5-[(2,6-difluoro-3,5-dimethoxyphenyl)methoxy]pyrimidin-2-yl]amino]pyrazol-1-yl]ethanol

ASP5878 is an oral active inhibitor of FGFR 1, 2, 3, and 4, with IC50 values of 0·47 nM, 0·6 nM, 0·74 nM and 3·5 nM for FGFR 1, 2, 3, and 4 kinase activity· ASP5878 has potential antineoplastic activity

ChemicalCAS1453208-66-6MW407.37FormulaC18H19F2N5O4
CAS number
1453208-66-6
Molecular weight
407.37
Formula
C18H19F2N5O4
Solubility
DMSO ： ≥ 250 mg/mL (613·69 mM);Water ： ＜ 0·1 mg/mL (insoluble)
InChIKey
VDZZYOJYLLNBTD-UHFFFAOYSA-N
Catalogue number
GC34476
Brand
GLPBIO
Computed properties PubChem CID 71736582 · XLogP 1.2 · TPSA 104 Ų · H-bond donors 2
XLogP
1.2
TPSA
104 Ų
H-bond donors
2
H-bond acceptors
10
Rotatable bonds
9
Heavy atoms
29

SMILES COC1=CC(=C(C(=C1F)COC2=CN=C(N=C2)NC3=CN(N=C3)CCO)F)OC

Computed descriptors from PubChem (CID 71736582), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.