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Chemical structure of ADH-503

GC60040

ADH-503

Also known as 4-[5-[(Z)-(3-benzyl-4-oxo-2-sulfanylidene-1,3-thiazolidin-5-ylidene)methyl]furan-2-yl]benzoate;2-hydroxyethyl(trimethyl)azanium

ADH-503 ((Z)-Leukadherin-1 choline) is an orally active and allosteric CD11b agonist· ADH-503 leads to the repolarization of tumor-associated macrophages, reduction in the number of tumor-infiltrating immunosuppressive myeloid cells, and enhances dendritic cell responses

ChemicalCAS2055362-74-6MW524.65FormulaC27H28N2O5S2
CAS number
2055362-74-6
Molecular weight
524.65
Formula
C27H28N2O5S2
Solubility
DMSO: 21·43 mg/mL (40·85 mM)
InChIKey
GOWDQYRMBCOOJR-JHMJKTBASA-M
Catalogue number
GC60040
Brand
GLPBIO
Computed properties PubChem CID 145711124 · TPSA 151 Ų · H-bond donors 1 · H-bond acceptors 7
TPSA
151 Ų
H-bond donors
1
H-bond acceptors
7
Rotatable bonds
6
Heavy atoms
36

SMILES C[N+](C)(C)CCO.C1=CC=C(C=C1)CN2C(=O)/C(=C/C3=CC=C(O3)C4=CC=C(C=C4)C(=O)[O-])/SC2=S

Computed descriptors from PubChem (CID 145711124), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
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Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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