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Chemical structure of KL 465

GC59470

KL 465

Also known as (2S,4R)-N-[[2-[2-[2-[2-[[4-(furan-2-carbonyl)piperazin-1-yl]methyl]-4-(1H-indazol-4-yl)phenoxy]ethoxy]ethoxy]-4-(4-methyl-1,3-thiazol-5-yl)phenyl]methyl]-4-hydroxy-1-[(2S)-3-methyl-2-(3-oxo-1H-isoindol-2-yl)butanoyl]pyrrolidine-2-carboxamide

MAGE-A3 Degrader (PROTAC®)

ChemicalCAS3057446-82-6MW1021.2FormulaC56H60N8O9S
CAS number
3057446-82-6
Molecular weight
1021.2
Formula
C56H60N8O9S
Solubility
DMSO: 51·06mg/mL
InChIKey
MQOTXOOWIOCPNH-IYCLWVRSSA-N
Catalogue number
GC59470
Brand
GLPBIO
Computed properties PubChem CID 175667470 · XLogP 6.2 · TPSA 224 Ų · H-bond donors 3
XLogP
6.2
TPSA
224 Ų
H-bond donors
3
H-bond acceptors
13
Rotatable bonds
19
Heavy atoms
74

SMILES CC1=C(SC=N1)C2=CC(=C(C=C2)CNC(=O)[C@@H]3C[C@H](CN3C(=O)[C@H](C(C)C)N4CC5=CC=CC=C5C4=O)O)OCCOCCOC6=C(C=C(C=C6)C7=C8C=NNC8=CC=C7)CN9CCN(CC9)C(=O)C1=CC=CO1

Computed descriptors from PubChem (CID 175667470), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.