Loading...
Chemical structure of SJF 1528

GC50748

SJF 1528

Also known as (2S,4R)-1-[(2S)-2-[[2-[2-[2-[4-[4-[3-chloro-4-[(3-fluorophenyl)methoxy]anilino]quinazolin-6-yl]phenoxy]ethoxy]ethoxy]acetyl]amino]-3,3-dimethylbutanoyl]-4-hydroxy-N-[[4-(4-methyl-1,3-thiazol-5-yl)phenyl]methyl]pyrrolidine-2-carboxamide

Potent EGFR Degrader (DC50 values are 39

ChemicalCAS2230821-38-0MW1030.61FormulaC55H57ClFN7O8S
CAS number
2230821-38-0
Molecular weight
1030.61
Formula
C55H57ClFN7O8S
Solubility
DMSO|103·06|100|
InChIKey
ZSCOIFSUFMYZEZ-YSWDPXALSA-N
Catalogue number
GC50748
Brand
GLPBIO
Computed properties PubChem CID 135157151 · XLogP 9 · TPSA 215 Ų · H-bond donors 4
XLogP
9
TPSA
215 Ų
H-bond donors
4
H-bond acceptors
14
Rotatable bonds
22
Heavy atoms
73

SMILES CC1=C(SC=N1)C2=CC=C(C=C2)CNC(=O)[C@@H]3C[C@H](CN3C(=O)[C@H](C(C)(C)C)NC(=O)COCCOCCOC4=CC=C(C=C4)C5=CC6=C(C=C5)N=CN=C6NC7=CC(=C(C=C7)OCC8=CC(=CC=C8)F)Cl)O

Computed descriptors from PubChem (CID 135157151), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.