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Chemical structure of XY 018

GC50389

XY 018

Also known as N-[4-[2-fluoro-4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]phenyl]-2-(2-nitrophenyl)acetamide

RORγ antagonist; inhibits AR expression

ChemicalCAS1873358-87-2MW516.36FormulaC23H15F7N2O4
CAS number
1873358-87-2
Molecular weight
516.36
Formula
C23H15F7N2O4
Solubility
DMSO : 100 mg/mL (193·66 mM; Need ultrasonic)
InChIKey
MNVXADPCMINSEC-UHFFFAOYSA-N
Catalogue number
GC50389
Brand
GLPBIO
Computed properties PubChem CID 130248006 · XLogP 5.4 · TPSA 95.2 Ų · H-bond donors 2
XLogP
5.4
TPSA
95.2 Ų
H-bond donors
2
H-bond acceptors
11
Rotatable bonds
5
Heavy atoms
36

SMILES C1=CC=C(C(=C1)CC(=O)NC2=CC=C(C=C2)C3=C(C=C(C=C3)C(C(F)(F)F)(C(F)(F)F)O)F)[N+](=O)[O-]

Computed descriptors from PubChem (CID 130248006), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

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