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Chemical structure of L-778,123

GC47533

L-778,123

Also known as 4-[[5-[[4-(3-chlorophenyl)-3-oxopiperazin-1-yl]methyl]imidazol-1-yl]methyl]benzonitrile

A dual inhibitor of FTase and GGTase I

ChemicalCAS183499-57-2MW405.9FormulaC22H20ClN5O
CAS number
183499-57-2
Molecular weight
405.9
Formula
C22H20ClN5O
Solubility
DMF： 30 mg/ml,DMSO： 30 mg/ml,DMSO：PBS (pH 7·2) (1：9)： 0·1 mg/ml,Ethanol： 10 mg/ml
InChIKey
JNUGFGAVPBYSHF-UHFFFAOYSA-N
Catalogue number
GC47533
Brand
GLPBIO
Computed properties PubChem CID 216454 · XLogP 2.7 · TPSA 65.2 Ų · H-bond donors 0
XLogP
2.7
TPSA
65.2 Ų
H-bond donors
0
H-bond acceptors
4
Rotatable bonds
5
Heavy atoms
29

SMILES C1CN(C(=O)CN1CC2=CN=CN2CC3=CC=C(C=C3)C#N)C4=CC(=CC=C4)Cl

Computed descriptors from PubChem (CID 216454), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.