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Chemical structure of L-765314

GC32670

L-765314

Also known as benzyl (2S)-4-(4-amino-6,7-dimethoxyquinazolin-2-yl)-2-(tert-butylcarbamoyl)piperazine-1-carboxylate

L-765314 is a potent and selective α1b adrenergic receptor antagonist with Kis of 5·4 nM and 2·0 nM for rat and human α1b adrenergic receptor, respectively

ChemicalCAS189349-50-6MW522.6FormulaC27H34N6O5
CAS number
189349-50-6
Molecular weight
522.6
Formula
C27H34N6O5
Solubility
DMSO ： 50 mg/mL (95·68 mM; Need ultrasonic)
InChIKey
CGWOIDCAGBKOQL-FQEVSTJZSA-N
Catalogue number
GC32670
Brand
GLPBIO
Computed properties PubChem CID 6603904 · XLogP 3.1 · TPSA 132 Ų · H-bond donors 2
XLogP
3.1
TPSA
132 Ų
H-bond donors
2
H-bond acceptors
9
Rotatable bonds
8
Heavy atoms
38

SMILES CC(C)(C)NC(=O)[C@@H]1CN(CCN1C(=O)OCC2=CC=CC=C2)C3=NC4=CC(=C(C=C4C(=N3)N)OC)OC

Computed descriptors from PubChem (CID 6603904), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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