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Chemical structure of Imatinib-d3

GC47452

Imatinib-d3

Also known as N-[4-methyl-3-[(4-pyridin-3-ylpyrimidin-2-yl)amino]phenyl]-4-[[4-(trideuteriomethyl)piperazin-1-yl]methyl]benzamide

Imatinib-d3 (STI571-d3) hydrochloride is the deuterium labeled Imatinib· Imatinib (STI571) is an orally bioavailable tyrosine kinases inhibitor that selectively inhibits BCR/ABL, v-Abl, PDGFR and c-kit kinase activity· Imatinib (STI571) works by binding close to the ATP binding site, locking it in a closed or self-inhibited conformation, therefore inhibiting the enzyme activity of the protein semicompetitively· Imatinib also is an inhibitor of SARS-CoV and MERS-CoV

ChemicalCAS1134803-18-1MW496.6FormulaC29H28D3N7O
CAS number
1134803-18-1
Molecular weight
496.6
Formula
C29H28D3N7O
Solubility
DMSO： slightly soluble,Methanol： slightly soluble
InChIKey
KTUFNOKKBVMGRW-BMSJAHLVSA-N
Catalogue number
GC47452
Brand
GLPBIO
Computed properties PubChem CID 25235817 · XLogP 3.5 · TPSA 86.3 Ų · H-bond donors 2
XLogP
3.5
TPSA
86.3 Ų
H-bond donors
2
H-bond acceptors
7
Rotatable bonds
7
Heavy atoms
37

SMILES [2H]C([2H])([2H])N1CCN(CC1)CC2=CC=C(C=C2)C(=O)NC3=CC(=C(C=C3)C)NC4=NC=CC(=N4)C5=CN=CC=C5

Computed descriptors from PubChem (CID 25235817), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.