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Chemical structure of Imatinib

GC10314

Imatinib

Also listed as Imatinib (STI571)

Imatinib (STI571) (STI571) is an orally bioavailable tyrosine kinases inhibitor that selectively inhibits BCR/ABL, v-Abl, PDGFR and c-kit kinase activity· Imatinib (STI571) (STI571) works by binding close to the ATP binding site, locking it in a closed or self-inhibited conformation, therefore inhibiting the enzyme activity of the protein semicompetitively· Imatinib (STI571) also is an inhibitor of SARS-CoV and MERS-CoV

ChemicalCAS152459-95-5MW493.6FormulaC29H31N7O
CAS number
152459-95-5
Molecular weight
493.6
Formula
C29H31N7O
Solubility
≥ 24·68mg/mL in DMSO
InChIKey
KTUFNOKKBVMGRW-UHFFFAOYSA-N
Catalogue number
GC10314
Brand
GLPBIO
Computed properties PubChem CID 5291 · XLogP 3.5 · TPSA 86.3 Ų · H-bond donors 2
XLogP
3.5
TPSA
86.3 Ų
H-bond donors
2
H-bond acceptors
7
Rotatable bonds
7
Heavy atoms
37

SMILES CC1=C(C=C(C=C1)NC(=O)C2=CC=C(C=C2)CN3CCN(CC3)C)NC4=NC=CC(=N4)C5=CN=CC=C5

Computed descriptors from PubChem (CID 5291), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.