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Chemical structure of Z-AEVD-FMK

GC45177

Z-AEVD-FMK

Also known as methyl (4S)-5-[[(2S)-1-[[(3S)-5-fluoro-1-methoxy-1,4-dioxopentan-3-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-5-oxo-4-[[(2S)-2-(phenylmethoxycarbonylamino)propanoyl]amino]pentanoate

Z-AEVD-FMK is an irreversible inhibitor of caspase-10 and related caspases

ChemicalCAS1135688-47-9MW610.6FormulaC28H39FN4O10
CAS number
1135688-47-9
Molecular weight
610.6
Formula
C28H39FN4O10
Solubility
10mg/mL in DMSO
InChIKey
CHZRBQFKZDGMTP-CDSYHYPYSA-N
Catalogue number
GC45177
Brand
GLPBIO
Computed properties PubChem CID 25108694 · XLogP 1.4 · TPSA 195 Ų · H-bond donors 4
XLogP
1.4
TPSA
195 Ų
H-bond donors
4
H-bond acceptors
11
Rotatable bonds
20
Heavy atoms
43

SMILES C[C@@H](C(=O)N[C@@H](CCC(=O)OC)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC(=O)OC)C(=O)CF)NC(=O)OCC1=CC=CC=C1

Computed descriptors from PubChem (CID 25108694), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.