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Chemical structure of Z-VAD-FMK

GC12861

Z-VAD-FMK

Also known as methyl (3S)-5-fluoro-3-[[(2S)-2-[[(2S)-3-methyl-2-(phenylmethoxycarbonylamino)butanoyl]amino]propanoyl]amino]-4-oxopentanoate

Z-VAD-FMK (Benzyloxycarbonyl-Val-Ala-Asp (OMe) fluoromethylketone), an ICE-like protease inhibitor, inhibits apoptosis by preventing the processing of CPP32 to its active form· [3]

ChemicalCAS187389-52-2MW467.49FormulaC22H30FN3O7
CAS number
187389-52-2
Molecular weight
467.49
Formula
C22H30FN3O7
Solubility
≥ 23·37mg/mL in DMSO
InChIKey
MIFGOLAMNLSLGH-QOKNQOGYSA-N
Catalogue number
GC12861
Brand
GLPBIO
Computed properties PubChem CID 5497174 · XLogP 1.9 · TPSA 140 Ų · H-bond donors 3
XLogP
1.9
TPSA
140 Ų
H-bond donors
3
H-bond acceptors
8
Rotatable bonds
14
Heavy atoms
33

SMILES C[C@@H](C(=O)N[C@@H](CC(=O)OC)C(=O)CF)NC(=O)[C@H](C(C)C)NC(=O)OCC1=CC=CC=C1

Computed descriptors from PubChem (CID 5497174), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

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Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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