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Chemical structure of Toll-Like Receptor 7 Ligand II

GC45063

Toll-Like Receptor 7 Ligand II

Also known as 6-amino-9-benzyl-2-(2-methoxyethoxy)-7H-purin-8-one

Toll-Like Receptor 7 Ligand II (CL-087) is a potent, oral actively TLR7 agonist

ChemicalCAS226907-52-4MW315.3FormulaC15H17N5O3
CAS number
226907-52-4
Molecular weight
315.3
Formula
C15H17N5O3
Solubility
DMF: 30 mg/ml,DMSO: 30 mg/ml,DMSO:PBS (pH 7·2) (1:1): 0·5 mg/ml
InChIKey
YYCDGEZXHXHLGW-UHFFFAOYSA-N
Catalogue number
GC45063
Brand
GLPBIO
Computed properties PubChem CID 10018576 · XLogP 0.7 · TPSA 103 Ų · H-bond donors 2
XLogP
0.7
TPSA
103 Ų
H-bond donors
2
H-bond acceptors
6
Rotatable bonds
6
Heavy atoms
23

SMILES COCCOC1=NC(=C2C(=N1)N(C(=O)N2)CC3=CC=CC=C3)N

Computed descriptors from PubChem (CID 10018576), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

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Documents
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