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Chemical structure of PQ-10

GC44673

PQ-10

Also known as 6,7-dimethoxy-4-(3-quinoxalin-2-yloxypyrrolidin-1-yl)quinazoline

PQ-10 is a potent and selective inhibitor of phosphodiesterase type 10 (PDE10; Ki = 4 nM)

ChemicalCAS927691-21-2MW403.4FormulaC22H21N5O3
CAS number
927691-21-2
Molecular weight
403.4
Formula
C22H21N5O3
Solubility
DMF： 25 mg/mL,DMF：PBS (pH 7·2) (1：20)： 0·04 mg/mL,DMSO： 16 mg/mL
InChIKey
UBIIFKJMNRPNMT-UHFFFAOYSA-N
Catalogue number
GC44673
Brand
GLPBIO
Computed properties PubChem CID 11704101 · XLogP 3.4 · TPSA 82.5 Ų · H-bond donors 0
XLogP
3.4
TPSA
82.5 Ų
H-bond donors
0
H-bond acceptors
8
Rotatable bonds
5
Heavy atoms
30

SMILES COC1=C(C=C2C(=C1)C(=NC=N2)N3CCC(C3)OC4=NC5=CC=CC=C5N=C4)OC

Computed descriptors from PubChem (CID 11704101), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
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Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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