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Chemical structure of PQR309

GC19300

PQR309

Also known as 5-(4,6-dimorpholin-4-yl-1,3,5-triazin-2-yl)-4-(trifluoromethyl)pyridin-2-amine

PQR309 is a potent, brain-penetrant, orally bioavailable, pan-class I PI3K/mTOR inhibitor with IC50s of 33nM, 451nM, 661nM, 708nM and 89nM for PI3Kα, PI3Kδ, PI3Kβ, PI3Kγ and mTOR, respectively

ChemicalCAS1225037-39-7MW411.38FormulaC17H20F3N7O2
CAS number
1225037-39-7
Molecular weight
411.38
Formula
C17H20F3N7O2
Solubility
DMSO ： ≥ 50 mg/mL (121·54 mM)
InChIKey
ADGGYDAFIHSYFI-UHFFFAOYSA-N
Catalogue number
GC19300
Brand
GLPBIO
Computed properties PubChem CID 58507717 · XLogP 1.3 · TPSA 103 Ų · H-bond donors 1
XLogP
1.3
TPSA
103 Ų
H-bond donors
1
H-bond acceptors
12
Rotatable bonds
3
Heavy atoms
29

SMILES C1COCCN1C2=NC(=NC(=N2)C3=CN=C(C=C3C(F)(F)F)N)N4CCOCC4

Computed descriptors from PubChem (CID 58507717), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.