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Chemical structure of NVP-AEW541 (hydrochloride)

GC44474

NVP-AEW541 (hydrochloride)

Also known as 7-[3-(azetidin-1-ylmethyl)cyclobutyl]-5-(3-phenylmethoxyphenyl)pyrrolo[2,3-d]pyrimidin-4-amine;dihydrochloride

Insulin-like growth factor 1 receptor (IGF-1R) is a receptor tyrosine kinase whose activation leads to angiogenesis as well as cell proliferation, survival, transformation, and metastasis

ChemicalCAS2320261-63-8MW512.5FormulaC27H29N5O•2HCl
CAS number
2320261-63-8
Molecular weight
512.5
Formula
C27H29N5O•2HCl
Solubility
Ethanol： 0·3 mg/ml,PBS (pH 7·2)： 2·5 mg/ml
InChIKey
XBUCKSAZHWFXGF-UHFFFAOYSA-N
Catalogue number
GC44474
Brand
GLPBIO
Computed properties PubChem CID 132285141 · TPSA 69.2 Ų · H-bond donors 3 · H-bond acceptors 5
TPSA
69.2 Ų
H-bond donors
3
H-bond acceptors
5
Rotatable bonds
7
Heavy atoms
35

SMILES C1CN(C1)CC2CC(C2)N3C=C(C4=C(N=CN=C43)N)C5=CC(=CC=C5)OCC6=CC=CC=C6.Cl.Cl

Computed descriptors from PubChem (CID 132285141), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
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Pricing
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Documents
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