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Chemical structure of CDK/CRK Inhibitor

GC43217

CDK/CRK Inhibitor

Also known as 1-(2,6-dichlorophenyl)-6-[[4-(2-hydroxyethoxy)phenyl]methyl]-3-propan-2-yl-5H-pyrazolo[5,4-d]pyrimidin-4-one

CDK/CRK inhibitor is an inhibitor of cyclin-dependent kinases (CDK) and CDK-related kinases (CRK) with IC50 values ranging from 9-839 nM in vitro

ChemicalCAS784211-09-2MW473.4FormulaC23H22Cl2N4O3
CAS number
784211-09-2
Molecular weight
473.4
Formula
C23H22Cl2N4O3
Solubility
DMF： 30 mg/ml,DMSO： 30 mg/ml,DMSO：PBS(pH 7·2) (1：4)： 0·2 mg/ml
InChIKey
RSQPNXBTPUXMQN-UHFFFAOYSA-N
Catalogue number
GC43217
Brand
GLPBIO
Computed properties PubChem CID 135473382 · XLogP 4.3 · TPSA 88.7 Ų · H-bond donors 2
XLogP
4.3
TPSA
88.7 Ų
H-bond donors
2
H-bond acceptors
5
Rotatable bonds
7
Heavy atoms
32

SMILES CC(C)C1=NN(C2=C1C(=O)NC(=N2)CC3=CC=C(C=C3)OCCO)C4=C(C=CC=C4Cl)Cl

Computed descriptors from PubChem (CID 135473382), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
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Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.