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Chemical structure of ADAMTS-5 Inhibitor

GC42722

ADAMTS-5 Inhibitor

Also known as (5Z)-5-[[5-[(4-chlorophenyl)methylsulfanyl]-1-methyl-3-(trifluoromethyl)pyrazol-4-yl]methylidene]-2-sulfanylidene-1,3-thiazolidin-4-one

A disintegrin and metalloproteinase with thrombospondin motifs 5 (ADAMTS-5) is an aggrecanase in that it cleaves aggrecan, a major proteoglycan in cartilage

ChemicalCAS929634-33-3MW449.9FormulaC16H11ClF3N3OS3
CAS number
929634-33-3
Molecular weight
449.9
Formula
C16H11ClF3N3OS3
Solubility
DMF： 30 mg/ml,DMSO： 30 mg/ml,DMSO：PBS (pH 7·2) (1：1)： 0·5 mg/ml,Ethanol： 20 mg/ml
InChIKey
CVYPRDPBCXSVBN-WDZFZDKYSA-N
Catalogue number
GC42722
Brand
GLPBIO
Computed properties PubChem CID 16664963 · XLogP 5 · TPSA 130 Ų · H-bond donors 1
XLogP
5
TPSA
130 Ų
H-bond donors
1
H-bond acceptors
8
Rotatable bonds
4
Heavy atoms
27

SMILES CN1C(=C(C(=N1)C(F)(F)F)/C=C\2/C(=O)NC(=S)S2)SCC3=CC=C(C=C3)Cl

Computed descriptors from PubChem (CID 16664963), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
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Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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