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Chemical structure of Pacritinib

GC41329

Pacritinib

Also known as (16E)-11-(2-pyrrolidin-1-ylethoxy)-14,19-dioxa-5,7,27-triazatetracyclo[19.3.1.12,6.18,12]heptacosa-1(24),2(27),3,5,8(26),9,11,16,21(25),22-decaene

FMS-like tyrosine kinase 3 (FLT3) and Janus kinase 2 (JAK2) are tyrosine kinases that mediate cytokine signaling and are frequently mutated in cancers, particularly acute myeloid leukemia

ChemicalCAS937272-79-2MW472.6FormulaC28H32N4O3
CAS number
937272-79-2
Molecular weight
472.6
Formula
C28H32N4O3
Solubility
DMSO： 0·5 mg/ml (slightly warmed)
InChIKey
HWXVIOGONBBTBY-ONEGZZNKSA-N
Catalogue number
GC41329
Brand
GLPBIO
Computed properties PubChem CID 46216796 · XLogP 3.8 · TPSA 68.7 Ų · H-bond donors 1
XLogP
3.8
TPSA
68.7 Ų
H-bond donors
1
H-bond acceptors
7
Rotatable bonds
4
Heavy atoms
35

SMILES C1CCN(C1)CCOC2=C3COC/C=C/COCC4=CC(=CC=C4)C5=NC(=NC=C5)NC(=C3)C=C2

Computed descriptors from PubChem (CID 46216796), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.