GC14676
Pacritinib
Also listed as Pacritinib (SB1518)
Pacritinib (SB1518) (SB1518) is a potent inhibitor of both wild-type JAK2 (IC50=23 nM) and JAK2V617F mutant (IC50=19 nM)· Pacritinib (SB1518) also inhibits FLT3 (IC50=22 nM) and its mutant FLT3D835Y (IC50=6 nM)
ChemicalCAS937272-79-2MW472.58FormulaC28H32N4O3
- CAS number
- 937272-79-2
- Molecular weight
- 472.58
- Formula
- C28H32N4O3
- Solubility
- ≥ 11·05mg/mL in DMSO with gentle warming
- InChIKey
- HWXVIOGONBBTBY-ONEGZZNKSA-N
- Catalogue number
- GC14676
- Brand
- GLPBIO
Computed properties PubChem CID 46216796 · XLogP 3.8 · TPSA 68.7 Ų · H-bond donors 1
- XLogP
- 3.8
- TPSA
- 68.7 Ų
- H-bond donors
- 1
- H-bond acceptors
- 7
- Rotatable bonds
- 4
- Heavy atoms
- 35
SMILES C1CCN(C1)CCOC2=C3COC/C=C/COCC4=CC(=CC=C4)C5=NC(=NC=C5)NC(=C3)C=C2
Computed descriptors from PubChem (CID 46216796), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.
Ordering in Israel
- Lead time
- Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
- Pricing
- Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
- Documents
- Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
- Who we serve
- Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.
- Questions
- WhatsApp · +972-55-990-7576 · orders@labo.co.il