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Chemical structure of PROTAC FKBP Degrader-3

GC39503

PROTAC FKBP Degrader-3

Also known as [(1R)-3-(3,4-dimethoxyphenyl)-1-[3-[2-[2-[2-[2-[2-[[(2S)-1-[(2S,4R)-4-hydroxy-2-[[4-(4-methyl-1,3-thiazol-5-yl)phenyl]methylcarbamoyl]pyrrolidin-1-yl]-3,3-dimethyl-1-oxobutan-2-yl]amino]-2-oxoethoxy]ethoxy]ethoxy]ethylamino]-2-oxoethoxy]phenyl]propyl] (2S)-1-[(2S)-2-(3,4,5-trimethoxyphenyl)butanoyl]piperidine-2-carboxylate

PROTAC FKBP Degrader-3 is a PROTAC that comprises a FKBP ligand binding group, a linker and an von Hippel-Lindau binding group· PROTAC FKBP Degrader-3 is a potent FKBP degrader

ChemicalCAS2079056-43-0MW1295.54FormulaC68H90N6O17S
CAS number
2079056-43-0
Molecular weight
1295.54
Formula
C68H90N6O17S
Solubility
DMSO： 25 mg/mL (19·30 mM)
InChIKey
CCQROXFLIRBPGZ-UKYCKITISA-N
Catalogue number
GC39503
Brand
GLPBIO
Computed properties PubChem CID 154805961 · XLogP 7.7 · TPSA 299 Ų · H-bond donors 4
XLogP
7.7
TPSA
299 Ų
H-bond donors
4
H-bond acceptors
19
Rotatable bonds
36
Heavy atoms
92

SMILES CC[C@@H](C1=CC(=C(C(=C1)OC)OC)OC)C(=O)N2CCCC[C@H]2C(=O)O[C@H](CCC3=CC(=C(C=C3)OC)OC)C4=CC(=CC=C4)OCC(=O)NCCOCCOCCOCC(=O)N[C@H](C(=O)N5C[C@@H](C[C@H]5C(=O)NCC6=CC=C(C=C6)C7=C(N=CS7)C)O)C(C)(C)C

Computed descriptors from PubChem (CID 154805961), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.