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Chemical structure of LP-935509

GC39256

LP-935509

Also known as propan-2-yl 4-[3-(2-methoxy-3-pyridinyl)pyrazolo[1,5-a]pyrimidin-5-yl]piperazine-1-carboxylate

LP-935509 is an orally active, potent, selective, ATP-competitive and brain-penetrant inhibitor of adaptor protein-2 associated kinase 1 (AAK1) with an IC50 of 3·3 nM and a Ki of 0·9 nM, respectively

ChemicalCAS1454555-29-3MW396.44FormulaC20H24N6O3
CAS number
1454555-29-3
Molecular weight
396.44
Formula
C20H24N6O3
Solubility
DMSO： 250 mg/mL (630·61 mM)
InChIKey
GOOYSJIWTIHOGW-UHFFFAOYSA-N
Catalogue number
GC39256
Brand
GLPBIO
Computed properties PubChem CID 86697436 · XLogP 2.1 · TPSA 85.1 Ų · H-bond donors 0
XLogP
2.1
TPSA
85.1 Ų
H-bond donors
0
H-bond acceptors
7
Rotatable bonds
5
Heavy atoms
29

SMILES CC(C)OC(=O)N1CCN(CC1)C2=NC3=C(C=NN3C=C2)C4=C(N=CC=C4)OC

Computed descriptors from PubChem (CID 86697436), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.