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Chemical structure of BPK-29 hydrochloride

GC38643

BPK-29 hydrochloride

Also known as N-benzyl-2-chloro-N-[1-(4-morpholin-4-ylbenzoyl)azepan-4-yl]acetamide;hydrochloride

BPK-29 hydrochloride is a specific ligand that disrupts the atypical orphan nuclear receptor NR0B1-protein (such RBM45 and SNW1) interactions by covalently modifying C274· BPK-29 hydrochloride impairs the anchorage-independent growth of KEAP1-mutant cancer cells

ChemicalCAS2444815-73-8MW506.46FormulaC26H33Cl2N3O3
CAS number
2444815-73-8
Molecular weight
506.46
Formula
C26H33Cl2N3O3
Solubility
DMSO: 62·5 mg/mL (123·41 mM)
InChIKey
FRNJMSGTTWKVPV-UHFFFAOYSA-N
Catalogue number
GC38643
Brand
GLPBIO
Computed properties PubChem CID 139035041 · TPSA 53.1 Ų · H-bond donors 1 · H-bond acceptors 4
TPSA
53.1 Ų
H-bond donors
1
H-bond acceptors
4
Rotatable bonds
6
Heavy atoms
34

SMILES C1CC(CCN(C1)C(=O)C2=CC=C(C=C2)N3CCOCC3)N(CC4=CC=CC=C4)C(=O)CCl.Cl

Computed descriptors from PubChem (CID 139035041), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
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Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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