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Chemical structure of BPN14770

GC35543

BPN14770

Also known as 2-[4-[[2-(3-chlorophenyl)-6-(trifluoromethyl)-4-pyridinyl]methyl]phenyl]acetic acid

BPN14770 (BPN14770) is a selective phosphodiesterase 4D (PDE4D) allosteric inhibitor with IC50s of 7·8 nM and 7·4 nM for PDE4D7 and PDE4D3, respectively

ChemicalCAS1606974-33-7MW405.8FormulaC21H15ClF3NO2
CAS number
1606974-33-7
Molecular weight
405.8
Formula
C21H15ClF3NO2
Solubility
DMSO： 260 mg/mL (640·71 mM)
InChIKey
LTSUMTMGJHPGFX-UHFFFAOYSA-N
Catalogue number
GC35543
Brand
GLPBIO
Computed properties PubChem CID 90111638 · XLogP 5.4 · TPSA 50.2 Ų · H-bond donors 1
XLogP
5.4
TPSA
50.2 Ų
H-bond donors
1
H-bond acceptors
6
Rotatable bonds
5
Heavy atoms
28

SMILES C1=CC(=CC(=C1)Cl)C2=NC(=CC(=C2)CC3=CC=C(C=C3)CC(=O)O)C(F)(F)F

Computed descriptors from PubChem (CID 90111638), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.