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Chemical structure of CP-547632 hydrochloride

GC38575

CP-547632 hydrochloride

Also known as 3-[(4-bromo-2,6-difluorophenyl)methoxy]-5-(4-pyrrolidin-1-ylbutylcarbamoylamino)-1,2-thiazole-4-carboxamide;hydrochloride

CP-547632 hydrochloride is an orally active, ATP-competitive and potent VEGFR-2 and FGF kinases inhibitor with IC50s of 11 nM and 9 nM, respectively· CP-547632 hydrochloride is selective for VEGFR2 and bFGF over EGFR, PDGFRβ, and related tyrosine kinases (TKs)· CP-547632 hydrochloride has antitumor efficacy

ChemicalCAS252003-71-7MW568.86FormulaC20H25BrClF2N5O3S
CAS number
252003-71-7
Molecular weight
568.86
Formula
C20H25BrClF2N5O3S
Solubility
DMSO: 38·33 mg/mL (67·38 mM); Water: < 0·1 mg/mL (insoluble)
InChIKey
NNPJZJJMQDXYGN-UHFFFAOYSA-N
Catalogue number
GC38575
Brand
GLPBIO
Computed properties PubChem CID 10370762 · TPSA 138 Ų · H-bond donors 4 · H-bond acceptors 8
TPSA
138 Ų
H-bond donors
4
H-bond acceptors
8
Rotatable bonds
10
Heavy atoms
33

SMILES C1CCN(C1)CCCCNC(=O)NC2=C(C(=NS2)OCC3=C(C=C(C=C3F)Br)F)C(=O)N.Cl

Computed descriptors from PubChem (CID 10370762), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.