GC38519
Ilorasertib hydrochloride
Also known as 1-[4-[4-amino-7-[1-(2-hydroxyethyl)pyrazol-4-yl]thieno[3,2-c]pyridin-3-yl]phenyl]-3-(3-fluorophenyl)urea;hydrochloride
Ilorasertib (ABT-348) hydrochloride is a potent, orally active and ATP-competitive aurora inhibitor with IC50s of116, 5, 1 nM for aurora A, aurora B, aurora C, respectively· Ilorasertib hydrochloride also is a potent VEGF, PDGF inhibitor· Ilorasertib hydrochloride has the potential for the research of acute myeloid leukemia (AML) and myelodysplastic syndrome (MDS)
ChemicalCAS1847485-91-9MW525FormulaC25H22ClFN6O2S
- CAS number
- 1847485-91-9
- Molecular weight
- 525
- Formula
- C25H22ClFN6O2S
- Solubility
- DMSO： 41·67 mg/mL (79·37 mM)
- InChIKey
- SUKMSIXFLFTNHO-UHFFFAOYSA-N
- Catalogue number
- GC38519
- Brand
- GLPBIO
Computed properties PubChem CID 54759636 · TPSA 146 Ų · H-bond donors 5 · H-bond acceptors 7
- TPSA
- 146 Ų
- H-bond donors
- 5
- H-bond acceptors
- 7
- Rotatable bonds
- 6
- Heavy atoms
- 36
SMILES C1=CC(=CC(=C1)F)NC(=O)NC2=CC=C(C=C2)C3=CSC4=C3C(=NC=C4C5=CN(N=C5)CCO)N.Cl
Computed descriptors from PubChem (CID 54759636), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.
Ordering in Israel
- Lead time
- Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
- Pricing
- Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
- Documents
- Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
- Who we serve
- Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.
- Questions
- WhatsApp · +972-55-990-7576 · orders@labo.co.il