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Chemical structure of Ilorasertib

GC34159

Ilorasertib

Also listed as Ilorasertib (ABT-348)

Ilorasertib (ABT-348) (ABT-348) is a potent, orally active and ATP-competitive aurora inhibitor with IC50s of116, 5, 1 nM for aurora A, aurora B, aurora C, respectively· Ilorasertib (ABT-348) also is a potent VEGF, PDGF inhibitor· Ilorasertib (ABT-348) has the potential for the research of acute myeloid leukemia (AML) and myelodysplastic syndrome (MDS)

ChemicalCAS1227939-82-3MW488.54FormulaC25H21FN6O2S
CAS number
1227939-82-3
Molecular weight
488.54
Formula
C25H21FN6O2S
Solubility
DMSO ： 83·33 mg/mL (170·57 mM);Water ： ＜ 0·1 mg/mL (insoluble)
InChIKey
WPHKIQPVPYJNAX-UHFFFAOYSA-N
Catalogue number
GC34159
Brand
GLPBIO
Computed properties PubChem CID 46207586 · XLogP 3 · TPSA 146 Ų · H-bond donors 4
XLogP
3
TPSA
146 Ų
H-bond donors
4
H-bond acceptors
7
Rotatable bonds
6
Heavy atoms
35

SMILES C1=CC(=CC(=C1)F)NC(=O)NC2=CC=C(C=C2)C3=CSC4=C3C(=NC=C4C5=CN(N=C5)CCO)N

Computed descriptors from PubChem (CID 46207586), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.