GC38353
APX-115
Also known as 5-phenyl-4-propyl-2-pyridin-2-yl-1H-pyrazol-3-one;hydrochloride
APX-115 (Ewha-18278) is a potent, orally active pan NADPH oxidase (Nox) inhibitor with Ki values of 1·08 μM, 0·57 μM, and 0·63 μM for Nox1, Nox2 and Nox4, respectively
ChemicalCAS1395946-75-4MW315.8FormulaC17H18ClN3O
- CAS number
- 1395946-75-4
- Molecular weight
- 315.8
- Formula
- C17H18ClN3O
- Solubility
- DMSO： ≥ 250 mg/mL (791·64 mM)
- InChIKey
- YEEIHSUMLNXRMI-UHFFFAOYSA-N
- Catalogue number
- GC38353
- Brand
- GLPBIO
Computed properties PubChem CID 60172240 · TPSA 45.2 Ų · H-bond donors 2 · H-bond acceptors 3
- TPSA
- 45.2 Ų
- H-bond donors
- 2
- H-bond acceptors
- 3
- Rotatable bonds
- 4
- Heavy atoms
- 22
SMILES CCCC1=C(NN(C1=O)C2=CC=CC=N2)C3=CC=CC=C3.Cl
Computed descriptors from PubChem (CID 60172240), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.
Ordering in Israel
- Lead time
- Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
- Pricing
- Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
- Documents
- Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
- Who we serve
- Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.
- Questions
- WhatsApp · +972-55-990-7576 · orders@labo.co.il