Loading...
Chemical structure of APY0201

GC31661

APY0201

Also known as N-[(E)-(3-methylphenyl)methylideneamino]-7-morpholin-4-yl-2-pyridin-4-ylpyrazolo[1,5-a]pyrimidin-5-amine

APY0201 is a potent PIKfyve inhibitor, which inhibits the conversion of PtdIns3P to PtdIns(3,5)P2 in the presence of in the presence of [33P]ATP with an IC50 of 5·2 nM

ChemicalCAS1232221-74-7MW413.48FormulaC23H23N7O
CAS number
1232221-74-7
Molecular weight
413.48
Formula
C23H23N7O
Solubility
DMSO ： ≥ 35 mg/mL (84·65 mM)
InChIKey
RFZQYGBLRIKROZ-PCLIKHOPSA-N
Catalogue number
GC31661
Brand
GLPBIO
Computed properties PubChem CID 56927660 · XLogP 3.3 · TPSA 79.9 Ų · H-bond donors 1
XLogP
3.3
TPSA
79.9 Ų
H-bond donors
1
H-bond acceptors
7
Rotatable bonds
5
Heavy atoms
31

SMILES CC1=CC(=CC=C1)/C=N/NC2=NC3=CC(=NN3C(=C2)N4CCOCC4)C5=CC=NC=C5

Computed descriptors from PubChem (CID 56927660), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.