Loading...
Chemical structure of Metarrestin

GC38201

Metarrestin

Also known as 4-(7-benzyl-4-imino-5,6-diphenylpyrrolo[2,3-d]pyrimidin-3-yl)cyclohexan-1-ol

Metarrestin (ML246) is an orally active, first-in-class and specific perinucleolar compartment inhibitor· Metarrestin disrupts the nucleolar structure and inhibits RNA polymerase (Pol) I transcription, at least in part by interacting with the translation elongation factor eEF1A2· Metarrestin blocks metastatic development and extends survival in mouse cancer models

ChemicalCAS1443414-10-5MW474.6FormulaC31H30N4O
CAS number
1443414-10-5
Molecular weight
474.6
Formula
C31H30N4O
Solubility
DMSO： 31·25 mg/mL (65·84 mM)
InChIKey
WSMXAUJFLWRPNT-UHFFFAOYSA-N
Catalogue number
GC38201
Brand
GLPBIO
Computed properties PubChem CID 50985821 · XLogP 5.6 · TPSA 64.6 Ų · H-bond donors 2
XLogP
5.6
TPSA
64.6 Ų
H-bond donors
2
H-bond acceptors
3
Rotatable bonds
5
Heavy atoms
36

SMILES C1CC(CCC1N2C=NC3=C(C2=N)C(=C(N3CC4=CC=CC=C4)C5=CC=CC=C5)C6=CC=CC=C6)O

Computed descriptors from PubChem (CID 50985821), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.