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Chemical structure of Tyrphostin AG30

GC38125

Tyrphostin AG30

Also known as (E)-2-cyano-3-(3,4-dihydroxyphenyl)prop-2-enoic acid

Tyrphostin AG30 (AG30) is a potent and selective EGFR tyrosine kinase inhibitor· Tyrphostin AG30 (AG30) selectively inhibits self renewal induction by c-ErbB, and is able to inhibit activation of STAT5 by c-ErbB in primary erythroblasts

ChemicalCAS122520-79-0MW205.17FormulaC10H7NO4
CAS number
122520-79-0
Molecular weight
205.17
Formula
C10H7NO4
Solubility
DMSO: 125 mg/mL (609·25 mM)
InChIKey
CJMWBHLWSMKFSM-XVNBXDOJSA-N
Catalogue number
GC38125
Brand
GLPBIO
Computed properties PubChem CID 5328793 · XLogP 1.1 · TPSA 102 Ų · H-bond donors 3
XLogP
1.1
TPSA
102 Ų
H-bond donors
3
H-bond acceptors
5
Rotatable bonds
2
Heavy atoms
15

SMILES C1=CC(=C(C=C1/C=C(\C#N)/C(=O)O)O)O

Computed descriptors from PubChem (CID 5328793), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

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