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Chemical structure of Tyrphostin 9

GC10758

Tyrphostin 9

Also known as 2-[(3,5-ditert-butyl-4-hydroxyphenyl)methylidene]propanedinitrile

Tyrphostin 9, a PDGFR inhibitor, is a potent inducer of mitochondrial fission

ChemicalCAS10537-47-0MW282.38FormulaC18H22N2O
CAS number
10537-47-0
Molecular weight
282.38
Formula
C18H22N2O
Solubility
≥ 14·1mg/mL in DMSO
InChIKey
MZOPWQKISXCCTP-UHFFFAOYSA-N
Catalogue number
GC10758
Brand
GLPBIO
Computed properties PubChem CID 5614 · XLogP 5 · TPSA 67.8 Ų · H-bond donors 1
XLogP
5
TPSA
67.8 Ų
H-bond donors
1
H-bond acceptors
3
Rotatable bonds
3
Heavy atoms
21

SMILES CC(C)(C)C1=CC(=CC(=C1O)C(C)(C)C)C=C(C#N)C#N

Computed descriptors from PubChem (CID 5614), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

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