GC37956
YUKA1
Also known as 4-[(3-methoxy-2-prop-2-enoxyphenyl)methylamino]-1H-1,2,4-triazole-5-thione
YUKA1 is a potent and cell permeable Lysine demethylase 5A (KDM5A) inhibitor, with an IC50 of 2·66 μM, less active on KDM5C (IC50, 7·12 μM), and is inactive on KDM5B, KDM6A or KDM6B· YUKA1 increases H3K4me3 levels in human cells with anti-cancer activity
ChemicalCAS708991-09-7MW292.36FormulaC13H16N4O2S
- CAS number
- 708991-09-7
- Molecular weight
- 292.36
- Formula
- C13H16N4O2S
- Solubility
- Soluble in DMSO
- InChIKey
- NHJCZZWENDYDEP-UHFFFAOYSA-N
- Catalogue number
- GC37956
- Brand
- GLPBIO
Computed properties PubChem CID 2215170 · XLogP 1.8 · TPSA 90.2 Ų · H-bond donors 2
- XLogP
- 1.8
- TPSA
- 90.2 Ų
- H-bond donors
- 2
- H-bond acceptors
- 5
- Rotatable bonds
- 7
- Heavy atoms
- 20
SMILES COC1=CC=CC(=C1OCC=C)CNN2C=NNC2=S
Computed descriptors from PubChem (CID 2215170), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.
Ordering in Israel
- Lead time
- Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
- Pricing
- Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
- Documents
- Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
- Who we serve
- Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.
- Questions
- WhatsApp · +972-55-990-7576 · orders@labo.co.il