GC37880
Vactosertib Hydrochloride
Also known as 2-fluoro-N-[[5-(6-methyl-2-pyridinyl)-4-([1,2,4]triazolo[1,5-a]pyridin-6-yl)-1H-imidazol-2-yl]methyl]aniline;hydrochloride
Vactosertib Hydrochloride (EW-7197 Hydrochloride) is a potent, orally active and ATP-competitive activin receptor-like kinase 5 (ALK5) inhibitor with an IC50 of 12·9 nM· Vactosertib Hydrochloride also inhibits ALK2 and ALK4 (IC50 of 17·3 nM) at nanomolar concentrations· Vactosertib Hydrochloride has potently antimetastatic activity and anticancer effect
ChemicalCAS1352610-25-3MW435.88FormulaC22H19ClFN7
- CAS number
- 1352610-25-3
- Molecular weight
- 435.88
- Formula
- C22H19ClFN7
- Solubility
- Water： 50 mg/mL (114·71 mM); DMSO： 50 mg/mL (114·71 mM)
- InChIKey
- UDRJLVATGDHMJM-UHFFFAOYSA-N
- Catalogue number
- GC37880
- Brand
- GLPBIO
Computed properties PubChem CID 54766014 · TPSA 83.8 Ų · H-bond donors 3 · H-bond acceptors 6
- TPSA
- 83.8 Ų
- H-bond donors
- 3
- H-bond acceptors
- 6
- Rotatable bonds
- 5
- Heavy atoms
- 31
SMILES CC1=NC(=CC=C1)C2=C(N=C(N2)CNC3=CC=CC=C3F)C4=CN5C(=NC=N5)C=C4.Cl
Computed descriptors from PubChem (CID 54766014), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.
Ordering in Israel
- Lead time
- Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
- Pricing
- Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
- Documents
- Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
- Who we serve
- Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.
- Questions
- WhatsApp · +972-55-990-7576 · orders@labo.co.il