Loading...
Chemical structure of Vacquinol-1 dihydrochloride

GC70107

Vacquinol-1 dihydrochloride

Also known as [2-(4-chlorophenyl)quinolin-4-yl]-piperidin-2-ylmethanol;dihydrochloride

Vacquinol-1 (NSC13316) dihydrochloride is a specific activator of MKK4 that can activate the MAPK pathway· Vacquinol-1 dihydrochloride specifically induces death of human glioblastoma cells (GC), slows tumor progression, and prolongs survival in a mouse model of glioblastoma· Vacquinol-1 dihydrochloride also induces apoptosis in hepatocellular carcinoma (HCC) cells

ChemicalCAS2309312-85-2MW425.78FormulaC21H23Cl3N2O
CAS number
2309312-85-2
Molecular weight
425.78
Formula
C21H23Cl3N2O
Solubility
DMSO : 25 mg/mL (58·72 mM; Need ultrasonic and warming)
InChIKey
JSUQSKIIFVRRHP-UHFFFAOYSA-N
Catalogue number
GC70107
Brand
GLPBIO
Computed properties PubChem CID 129896712 · TPSA 45.2 Ų · H-bond donors 4 · H-bond acceptors 3
TPSA
45.2 Ų
H-bond donors
4
H-bond acceptors
3
Rotatable bonds
3
Heavy atoms
27

SMILES C1CCNC(C1)C(C2=CC(=NC3=CC=CC=C32)C4=CC=C(C=C4)Cl)O.Cl.Cl

Computed descriptors from PubChem (CID 129896712), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.