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Chemical structure of TR-14035

GC37818

TR-14035

Also known as (2S)-2-[(2,6-dichlorobenzoyl)amino]-3-[4-(2,6-dimethoxyphenyl)phenyl]propanoic acid

TR-14035 is a orally active dual α4β7/α4β1 integrin antagonist, with IC50 s of 7 nM and 87 nM for α4β7 and α4β1, respectively

ChemicalCAS232271-19-1MW474.33FormulaC24H21Cl2NO5
CAS number
232271-19-1
Molecular weight
474.33
Formula
C24H21Cl2NO5
Solubility
DMSO: ≥ 41 mg/mL (86·44 mM)
InChIKey
DRSJLVGDSNWQBI-SFHVURJKSA-N
Catalogue number
GC37818
Brand
GLPBIO
Computed properties PubChem CID 9912743 · XLogP 5.6 · TPSA 84.9 Ų · H-bond donors 2
XLogP
5.6
TPSA
84.9 Ų
H-bond donors
2
H-bond acceptors
5
Rotatable bonds
8
Heavy atoms
32

SMILES COC1=C(C(=CC=C1)OC)C2=CC=C(C=C2)C[C@@H](C(=O)O)NC(=O)C3=C(C=CC=C3Cl)Cl

Computed descriptors from PubChem (CID 9912743), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.