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Chemical structure of TH588 hydrochloride

GC37777

TH588 hydrochloride

Also known as 4-N-cyclopropyl-6-(2,3-dichlorophenyl)pyrimidine-2,4-diamine;hydrochloride

TH588 hydrochloride is first-in-class nudix hydrolase family inhibitor that potently and selectively engage and inhibit the MTH1 (IC50= 5 nM)

ChemicalCAS1640282-30-9MW331.63FormulaC13H13Cl3N4
CAS number
1640282-30-9
Molecular weight
331.63
Formula
C13H13Cl3N4
Solubility
Soluble in DMSO
InChIKey
FBHMEHNWFXCSKE-UHFFFAOYSA-N
Catalogue number
GC37777
Brand
GLPBIO
Computed properties PubChem CID 91826507 · TPSA 63.8 Ų · H-bond donors 3 · H-bond acceptors 4
TPSA
63.8 Ų
H-bond donors
3
H-bond acceptors
4
Rotatable bonds
3
Heavy atoms
20

SMILES C1CC1NC2=NC(=NC(=C2)C3=C(C(=CC=C3)Cl)Cl)N.Cl

Computed descriptors from PubChem (CID 91826507), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.