Loading...
Chemical structure of TAK-960 dihydrochloride

GC37725

TAK-960 dihydrochloride

TAK-960 dihydrochloride is an orally available, selective inhibitor of polo-like kinase 1 (PLK1), with an IC50 of 0·8 nM· TAK-960 dihydrochloride also shows inhibitory activities against PLK2 and PLK3, with IC50s of 16·9 and 50·2 nM, respectively· TAK-960 dihydrochloride inhibits proliferation of multiple cancer cell lines and exhibits significant efficacy against multiple tumor xenografts

ChemicalMW634.52FormulaC27H36Cl2F3N7O3
CAS number
Molecular weight
634.52
Formula
C27H36Cl2F3N7O3
Solubility
DMSO: ≥ 98·57 mg/mL (155·35 mM)
Catalogue number
GC37725
Brand
GLPBIO

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.