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Chemical structure of SB-277011

GC37600

SB-277011

Also known as N-[4-[2-(6-cyano-3,4-dihydro-1H-isoquinolin-2-yl)ethyl]cyclohexyl]quinoline-4-carboxamide

SB-277011 is a potent and delective dopamine D3 receptor antagonist (pKi values are 8·0, 6·0, 5·0 and ＜5·2 for D3, D2, 5-HT1D and 5-HT1B respectively); brain penetrant

ChemicalCAS215803-78-4MW438.56FormulaC28H30N4O
CAS number
215803-78-4
Molecular weight
438.56
Formula
C28H30N4O
Solubility
Soluble in DMSO
InChIKey
OLWRVVHPJFLNPW-UHFFFAOYSA-N
Catalogue number
GC37600
Brand
GLPBIO
Computed properties PubChem CID 5311096 · XLogP 4.6 · TPSA 69 Ų · H-bond donors 1
XLogP
4.6
TPSA
69 Ų
H-bond donors
1
H-bond acceptors
4
Rotatable bonds
5
Heavy atoms
33

SMILES C1CC(CCC1CCN2CCC3=C(C2)C=CC(=C3)C#N)NC(=O)C4=CC=NC5=CC=CC=C45

Computed descriptors from PubChem (CID 5311096), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.