GC37575
Ruxolitinib sulfate
Also known as (3R)-3-cyclopentyl-3-[4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)pyrazol-1-yl]propanenitrile;sulfuric acid
Ruxolitinib sulfate (INCB018424 sulfate) is the first potent, selective JAK1/2 inhibitor to enter the clinic with IC50s of 3·3 nM/2·8 nM, and has > 130-fold selectivity for JAK1/2 versus JAK3
ChemicalCAS1092939-16-6MW404.44FormulaC17H20N6O4S
- CAS number
- 1092939-16-6
- Molecular weight
- 404.44
- Formula
- C17H20N6O4S
- Solubility
- Soluble in DMSO
- InChIKey
- LGJWVXWQCTZSGC-XFULWGLBSA-N
- Catalogue number
- GC37575
- Brand
- GLPBIO
Computed properties PubChem CID 25127111 · TPSA 166 Ų · H-bond donors 3 · H-bond acceptors 8
- TPSA
- 166 Ų
- H-bond donors
- 3
- H-bond acceptors
- 8
- Rotatable bonds
- 4
- Heavy atoms
- 28
SMILES C1CCC(C1)[C@@H](CC#N)N2C=C(C=N2)C3=C4C=CNC4=NC=N3.OS(=O)(=O)O
Computed descriptors from PubChem (CID 25127111), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.
Ordering in Israel
- Lead time
- Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
- Pricing
- Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
- Documents
- Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
- Who we serve
- Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.
- Questions
- WhatsApp · +972-55-990-7576 · orders@labo.co.il