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Chemical structure of PI3Kα/mTOR-IN-1

GC36909

PI3Kα/mTOR-IN-1

Also known as 2-amino-8-cyclopentyl-4-methyl-6-(1H-pyrazol-4-yl)pyrido[2,3-d]pyrimidin-7-one

PI3Kα/mTOR-IN-1 is a potent PI3Kα/mTOR dual inhibitor, with an IC50 of 7 nM for PI3Kα in a cell assay, and Kis of 10·6 nM and 12·5 nM for mTOR and PI3Kα in a cell free assay , respectively

ChemicalCAS1013098-90-2MW310.35FormulaC16H18N6O
CAS number
1013098-90-2
Molecular weight
310.35
Formula
C16H18N6O
Solubility
Soluble in DMSO
InChIKey
VMGMCPMGGFUNMP-UHFFFAOYSA-N
Catalogue number
GC36909
Brand
GLPBIO
Computed properties PubChem CID 59258964 · XLogP 1.4 · TPSA 101 Ų · H-bond donors 2
XLogP
1.4
TPSA
101 Ų
H-bond donors
2
H-bond acceptors
5
Rotatable bonds
2
Heavy atoms
23

SMILES CC1=C2C=C(C(=O)N(C2=NC(=N1)N)C3CCCC3)C4=CNN=C4

Computed descriptors from PubChem (CID 59258964), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.