Loading...
Chemical structure of PF-04937319

GC36881

PF-04937319

Also known as N,N-dimethyl-5-[[2-methyl-6-[(5-methylpyrazin-2-yl)carbamoyl]-1-benzofuran-4-yl]oxy]pyrimidine-2-carboxamide

PF-04937319 is a glucokinase activator (GKA) with EC50 value of 154·4 ?μM, one of the most promising strategies for the treatment of type 2 diabetes mellitus

ChemicalCAS1245603-92-2MW432.43FormulaC22H20N6O4
CAS number
1245603-92-2
Molecular weight
432.43
Formula
C22H20N6O4
Solubility
DMSO ： 100 mg/mL (231·25 mM; Need ultrasonic)
InChIKey
MASKQITXHVYVFL-UHFFFAOYSA-N
Catalogue number
GC36881
Brand
GLPBIO
Computed properties PubChem CID 46916694 · XLogP 1.8 · TPSA 123 Ų · H-bond donors 1
XLogP
1.8
TPSA
123 Ų
H-bond donors
1
H-bond acceptors
8
Rotatable bonds
5
Heavy atoms
32

SMILES CC1=CC2=C(O1)C=C(C=C2OC3=CN=C(N=C3)C(=O)N(C)C)C(=O)NC4=NC=C(N=C4)C

Computed descriptors from PubChem (CID 46916694), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.