GC32701
PF-04957325
Also known as 3-[[(2R)-4-(1,3-thiazol-2-ylmethyl)morpholin-2-yl]methyl]-5-(trifluoromethyl)triazolo[4,5-d]pyrimidin-7-amine
PF-04957325 is a highly potent and selective PDE8 inhibitor, with IC50s of 0·7 nM and 0·3 nM for PDE8A and PDE8B, respectively
ChemicalCAS1305115-80-3MW400.38FormulaC14H15F3N8OS
- CAS number
- 1305115-80-3
- Molecular weight
- 400.38
- Formula
- C14H15F3N8OS
- Solubility
- DMSO ： 9·9 mg/mL (24·73 mM)
- InChIKey
- VNLPYEMGHGDRRZ-MRVPVSSYSA-N
- Catalogue number
- GC32701
- Brand
- GLPBIO
Computed properties PubChem CID 52938379 · XLogP 0.5 · TPSA 136 Ų · H-bond donors 1
- XLogP
- 0.5
- TPSA
- 136 Ų
- H-bond donors
- 1
- H-bond acceptors
- 12
- Rotatable bonds
- 4
- Heavy atoms
- 27
SMILES C1CO[C@H](CN1CC2=NC=CS2)CN3C4=NC(=NC(=C4N=N3)N)C(F)(F)F
Computed descriptors from PubChem (CID 52938379), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.
Ordering in Israel
- Lead time
- Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
- Pricing
- Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
- Documents
- Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
- Who we serve
- Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.
- Questions
- WhatsApp · +972-55-990-7576 · orders@labo.co.il